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Article

HMGN2 accelerates the proliferation and cell cycle progression of glioblastoma by regulating CDC20 expression

13 Sept 2024

Abstract excerpt

Gliomas represent the most common primary malignant intracranial tumors in adults. Despite recent advances in treatment, the prognosis of patients with glioblastoma remains poor. Epigenetic abnormalities, the hallmarks of various types of cancer, contribute to the dysregulated expression of cancer-related genes. Post-translational modification of histones plays a pivotal role in cancer development and progression...

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PMID: 40092489
DOI: 10.1016/j.gendis.2024.101433

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