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Article

Combination of CYP2C19 genotype with non-genetic factors evoking phenoconversion improves phenotype prediction.

Pharmacological reports : PR - 1 Jun 2018

Kiss Ádám Ferenc, Vaskó Dorottya, Déri Máté Tamás, Tóth Katalin, Monostory Katalin

Abstract excerpt

BACKGROUND: CYP2C19 is an important drug-metabolizing enzyme, responsible for metabolism of approximately 10% of the drugs on the market. Large inter-individual differences exist in metabolic activities, which are primarily attributed to genetic polymorphism of CYP2C19 gene. Conflicting results have been published about the role of CYP2C19 polymorphisms in metabolism of CYP2C19 substrates and clinical outcomes;...

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PMID: 29665549
DOI: 10.1016/j.pharep.2017.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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