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Article

CD206-positive myeloid cells bind galectin-9 and promote a tumor-supportive microenvironment.

The Journal of pathology - 1 Aug 2018

Enninga Elizabeth Ann L, Chatzopoulos Kyriakos, Butterfield John T, Sutor Shari L, Leontovich Alexey A, Nevala Wendy K, Flotte Thomas J, Markovic Svetomir N

Abstract excerpt

In patients with metastatic melanoma, high blood levels of galectin-9 are correlated with worse overall survival and a bias towards a Th2 inflammatory state supportive of tumor growth. Although galectin-9 signaling through TIM3 on T cells has been described, less is known about the interaction of galectin-9 with macrophages. We aimed to determine whether galectin-9 is a binding partner of CD206 on macrophages and...

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Share to Chemokine CCL2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lectins, C-Type

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Source

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Identifiers

PMID: 29732570
DOI: 10.1002/path.5093
PMCID: PMC6935353

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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