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Possible role of galectin‐9 in cell aggregation and apoptosis of human melanoma cell lines and its clinical significance

23 May 2002

Abstract excerpt

Galectin-9 expression was examined in 6 human melanoma cell lines. Among them, MM-BP proliferated with colony formation, but MM-RU failed. RT-PCR analysis revealed evident expression of galectin-9 mRNA in MM-BP but not in MM-RU. MM-BP expressed galectin-9 protein both on the surface and in the cytoplasm, whereas MM-RU expressed it only weakly in the cytoplasm. Exogenous galectin-9 induced in vitro both cell...

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PMID: 12115481
DOI: 10.1002/ijc.10436

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