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Galectin-9 – ligand axis: an emerging therapeutic target for multiple myeloma

25 Sept 2024

Abstract excerpt

Galectin-9 (Gal-9) is a tandem-repeat galectin with diverse roles in immune homeostasis, inflammation, malignancy, and autoimmune diseases. In cancer, Gal-9 displays variable expression patterns across different tumor types. Its interactions with multiple binding partners, both intracellularly and extracellularly, influence key cellular processes, including immune cell modulation and tumor microenvironment...

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PMID: 39386209
DOI: 10.3389/fimmu.2024.1469794

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