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Article

The cortical excitability profile of patients with the G209A SNCA mutation versus patients with sporadic Parkinson's disease: A transcranial magnetic stimulation study.

Neurophysiologie clinique = Clinical neurophysiology - 1 Sept 2018

Kimiskidis Vasilios K, Papayiannopoulos Sotirios, Sotirakoglou Kyriaki, Karakasis Haralambos, Katsarou Zoe, Kazis Dimitrios A, Papaliagkas Vasileios, Gatzonis Stylianos, Papadimitriou Alexandros, Hadjigeorgiou Georgios, Bostanjopoulou Sevasti

Abstract excerpt

Mutations in the α-synuclein gene are a rare cause of Parkinson's disease. We investigated, by single-pulse TMS, the cortical excitability profile of nine α-synuclein patients in comparison with 24 idiopathic PD patients, subdivided into "akinetic" (n=17) and "tremor-dominant" (n=7) subgroups. The comparative assessment of rest motor threshold, active MEP and Silent Period Input/Output curves indicated that the...

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Identifiers

PMID: 29729894
DOI: 10.1016/j.neucli.2018.04.002

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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