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Article

Use of Functional Magnetic Resonance Imaging to Assess How Motor Phenotypes of Parkinson's Disease Respond to Deep Brain Stimulation.

Neuromodulation : journal of the International Neuromodulation Society - 1 Jun 2020

DiMarzio Marisa, Madhavan Radhika, Joel Suresh, Hancu Ileana, Fiveland Eric, Prusik Julia, Gillogly Michael, Rashid Tanweer, MacDonell Jacquelyn, Ashe Jeffrey, Telkes Ilknur, Feustel Paul, Staudt Michael D, Shin Damian S, Durphy Jennifer, Hwang Roy, Hanspal Era, Pilitsis Julie G

Abstract excerpt

BACKGROUND: Deep brain stimulation (DBS) is a well-accepted treatment of Parkinson's disease (PD). Motor phenotypes include tremor-dominant (TD), akinesia-rigidity (AR), and postural instability gait disorder (PIGD). The mechanism of action in how DBS modulates motor symptom relief remains unknown. OBJECTIVE: Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) was used to determine...

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PMID: 32369255
DOI: 10.1111/ner.13160

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