Article
Distinct phenotypes of stimulation-induced dysarthria represent different cortical networks in STN-DBS.
Parkinsonism & related disorders - 1 Apr 2023
Lange Florian, Eldebakey Hazem, Hilgenberg Alexandra, Weigl Benedikt, Eckert Marie, DeSunda Angela, Neugebauer Hermann, Peach Robert, Roothans Jonas, Volkmann Jens, Reich Martin M
Abstract excerpt
BACKGROUND: Deep brain stimulation of the subthalamic nucleus is an effective treatment of Parkinson's disease, yet it is often associated with a general deterioration of speech intelligibility. Clustering the phenotypes of dysarthria has been proposed as a strategy to tackle these stimulation-induced speech problems. METHODS: In this study, we examine a cohort of 24 patients to test the real-life application of...
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