Article
Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells.
Molecular and cellular neurosciences - 1 Jun 2016
Watmuff Bradley, Berkovitch Shaunna S, Huang Joanne H, Iaconelli Jonathan, Toffel Steven, Karmacharya Rakesh
Abstract excerpt
Schizophrenia and bipolar disorder are complex psychiatric disorders that present unique challenges in the study of disease biology. There are no objective biological phenotypes for these disorders, which are characterized by complex genetics and prominent roles for gene-environment interactions. The study of the neurobiology underlying these severe psychiatric disorders has been hindered by the lack of access to...
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