GAD65 Promoter Polymorphism rs2236418 Modulates Harm Avoidance in Women via Inhibition/Excitation Balance in the Rostral ACC.

doi:10.1523/JNEUROSCI.1985-17.2018

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Article

GAD65 Promoter Polymorphism rs2236418 Modulates Harm Avoidance in Women via Inhibition/Excitation Balance in the Rostral ACC.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 May 2018

Colic Lejla, Li Meng, Demenescu Liliana Ramona, Li Shija, Müller Iris, Richter Anni, Behnisch Gusalija, Seidenbecher Constanze I, Speck Oliver, Schott Björn H, Stork Oliver, Walter Martin

Abstract excerpt

Anxiety disorders are common and debilitating conditions with higher prevalence in women. However, factors that predispose women to anxiety phenotypes are not clarified. Here we investigated potential contribution of the single nucleotide polymorphism rs2236418 in GAD2 gene to changes in regional inhibition/excitation balance, anxiety-like traits, and related neural activity in both sexes. One hundred and five...

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Identifiers

PMID: 29724796
DOI: 10.1523/JNEUROSCI.1985-17.2018
PMCID: PMC6705942

Genes

GAD2
GAD1
GLS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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