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Article

Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2009

Unschuld Paul G, Ising Marcus, Specht Michael, Erhardt Angelika, Ripke Stephan, Heck Angela, Kloiber Stefan, Straub Verica, Brueckl Tanja, Müller-Myhsok Bertram, Holsboer Florian, Binder Elisabeth B

Abstract excerpt

Glutamate decarboxylase (GAD) is the rate limiting enzyme for conversion of glutamic acid to gamma-aminobutyric acid (GABA). The GAD 65 kDa isoform is encoded by the gene GAD2 and is mainly expressed in synaptic terminals. It serves as an apoenzyme, which shows enhanced availability in situations...

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Identifiers

PMID: 19229853
DOI: 10.1002/ajmg.b.30938

Genes

GAD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19229853-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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