Article
Neural mechanisms of oxytocin receptor gene mediating anxiety-related temperament.
Brain structure & function - 1 Sept 2014
Wang Junping, Qin Wen, Liu Bing, Zhou Yuan, Wang Dawei, Zhang Yunting, Jiang Tianzi, Yu Chunshui
Abstract excerpt
A common variant (rs53576) of the OXTR gene has been implicated in a number of socio-emotional phenotypes, such as anxiety-related behavior. Previous studies have demonstrated that A-allele carriers have higher levels of physiological and dispositional stress reactivity and depressive symptomatology compared to those with the GG genotype, but the mediating neural mechanisms remain poorly understood. We combined...
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