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Article

Attenuated Phenotype and Immunogenic Characteristics of a Mutated Herpes Simplex Virus 1 Strain in the Rhesus Macaque.

Viruses - 2 May 2018

Fan Shengtao, Xu Xingli, Liao Yun, Wang Yongrong, Wang Jianbin, Feng Min, Wang Lichun, Zhang Ying, He Zhanlong, Yang Fengmei, Fraser Nigel W, Li Qihan

Abstract excerpt

Herpes simplex virus type 1(HSV-1) presents a conundrum to public health worldwide because of its specific pathogenicity and clinical features. Some experimental vaccines, such as the recombinant viral glycoproteins, exhibit the viral immunogenicity of a host-specific immune response, but none of these has achieved a valid epidemiological protective efficacy in the human population. In the present study, we...

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Source

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Identifiers

PMID: 29724057
DOI: 10.3390/v10050234
PMCID: PMC5977227

Genes

LAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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