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Genome Sequence of Herpes Simplex Virus 1 Strain McKrae

9 Aug 2012

Abstract excerpt

The herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent compared to other wild-type strains of HSV-1. To help us better understand the genetic determinants that lead to differences in the pathogenicity of McKrae and other HSV-1 strains, we sequenced its genome. Comparing the sequence of McKrae's genome to that of strain 17 revealed that the genomes differ by at least 752 single nucleotide...

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PMID: 22879612
DOI: 10.1128/jvi.01469-12

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