Article
Sequence and comparative analysis of the genome of HSV-1 strain McKrae.
Virology - 25 Nov 2012
Watson G, Xu W, Reed A, Babra B, Putman T, Wick E, Wechsler S L, Rohrmann G F, Jin L
Abstract excerpt
Ocular infection by HSV-1 strain McKrae is neurovirulent in both mice and rabbits and causes fatal encephalitis in approximately 50% of animals. In addition, it spontaneously reactivates with high frequency relative to other HSV-1 strains in rabbits. We sequenced the McKrae strain genome and compared its coding protein sequences with those of six other HSV-1 strains. Most of the 74 predicted protein sequences are...
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