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Article

A novel cross‐species inhibitor to study the function of CatSper Ca2+ channels in sperm

3 May 2018

Abstract excerpt

Background and Purpose Sperm from many species share the sperm‐specific Ca2+ channel CatSper that controls the intracellular Ca2+ concentration and, thereby, the swimming behaviour. A growing body of evidence suggests that the mechanisms controlling the activity of CatSper and its role during fertilization differ among species. A lack of suitable pharmacological tools has hampered the elucidation of the function...

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PMID: 29723408
DOI: 10.1111/bph.14355

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