Article
Revisiting the action of steroids and triterpenoids on the human sperm Ca2+ channel CatSper
1 Sept 2020
Abstract excerpt
The sperm-specific Ca2+ channel CatSper (cation channel of sperm) is vital for male fertility. Contradictory findings have been published on the regulation of human CatSper by the endogenous steroids estradiol, testosterone and hydrocortisone, as well as the plant triterpenoids, lupeol and pristimerin. The aim of this study was to elucidate this controversy by investigating the action of these steroids and plant...
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