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Article

Human sperm ion channel (dys)function: implications for fertilization

20 Aug 2019

Abstract excerpt

BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in sperm for fertility. In both species, the calcium current is carried by the highly complex cation channel of sperm (CatSper). In mouse sperm, the potassium...

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PMID: 31665287
DOI: 10.1093/humupd/dmz032

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