Article
IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing.
Genome biology and evolution - 1 Apr 2018
Jobin Matthew, Schurz Haiko, Henn Brenna M
Abstract excerpt
We introduce IMPUTOR, software for phylogenetically aware imputation of missing haploid nonrecombining genomic data. Targeted for next-generation sequencing data, IMPUTOR uses the principle of parsimony to impute data marked as missing due to low coverage. Along with efficiently imputing missing variant genotypes, IMPUTOR is capable of reliably and accurately correcting many nonmissing sites that represent...
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