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Article

Archaic ancestry inference in imputed ancient human genomes.

Nature communications - 6 Aug 2026

Capodiferro Marco Rosario, Planche Léo, Breslin Emily M, Ongaro Linda, Ávila-Arcos María C, Jay Flora, Cassidy Lara M, Huerta-Sanchez Emilia

Abstract excerpt

When modern humans expanded from Africa into Eurasia, they interbred with archaic hominins such as Neanderthals and Denisovans. This introgression shaped human evolution, yet most insights have been gained from present-day genomes, leaving little known about how archaic variants evolved after interbreeding. Ancient genomes offer a direct view of this process, but low coverage and poor quality have limited their...

Read the complete abstract on PubMed

Topics

Humans
Genome, Human
Haplotypes
Animals
Neanderthals
Hominidae
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

DNA, Ancient

Evolution, Molecular

Genetics, Population

Genetic Introgression

Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42693085
DOI: 10.1038/s41467-026-76204-0
PMCID: PMC13542231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

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