Article
Highly Accurate and Efficient Data-Driven Methods for Genotype Imputation.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Choudhury Olivia, Chakrabarty Ankush, Emrich Scott J
Abstract excerpt
High-throughput sequencing techniques have generated massive quantities of genotype data. Haplotype phasing has proven to be a useful and effective method for analyzing these data. However, the quality of phasing is undermined due to missing information. Imputation provides an effective means of improving the underlying genotype information. For model organisms, imputation can rely on an available reference...
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