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Article

miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma

3 May 2018

Abstract excerpt

Asthma is characterized by a chronic inflammation and remodeling of the airways. Although inflammation can be controlled, therapeutic options to revert remodeling do not exist. Thus, there is a large and unmet need to understand the underlying molecular mechanisms to develop novel therapies. We previously identified a pivotal role for miR-142-3p in regulating airway smooth muscle (ASM) precursor cell...

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PMID: 29722559
DOI: 10.1152/ajplung.00113.2018

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