Article
Follistatin-related protein 1 in asthma: miR-200b-3p interactions affect airway remodeling and inflammation phenotype.
International immunopharmacology - 1 Aug 2022
Liu Fen, Zhang Jintao, Zhang Dong, Qi Qian, Cui Wenjing, Pan Yun, Liu Xiaofei, Xu Jiawei, Qiao Xinrui, Wang Zihan, Dong Liang
Abstract excerpt
Follistatin-related protein 1 (FSTL1) is significantly associated with the asthma severity and outcome in humans and diverse mouse models of asthma. Previous studies have also suggested that FSTL1 could activate autophagy and NLRP3, thus playing as a causative agent in the asthma progression. However, mechanisms that regulate airway epithelial cell-specific FSTL1 expression and function in asthma are unknown....
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