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Article

β-catenin as a regulator and therapeutic target for asthmatic airway remodeling

8 Jul 2014

Abstract excerpt

INTRODUCTION: Pathological alteration in the airway structure, termed as airway remodeling, is a hallmark feature of individuals with asthma and has been described to negatively impact lung function in asthmatics. Recent studies have raised considerable interest in the regulatory role of β-catenin in remodeling asthmatic airways. The WNT/β-catenin signaling pathway is the key to normal lung development and...

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PMID: 25005144
DOI: 10.1517/14728222.2014.934813

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