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Article

Canonical WNT pathway is activated in the airway epithelium in chronic obstructive pulmonary disease

9 Oct 2020

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a devastating lung disease, mainly due to cigarette smoking, which represents the third cause of mortality worldwide. The mechanisms driving its epithelial salient features remain largely elusive. We aimed to evaluate the activation and the role of the canonical, β-catenin-dependant WNT pathway in the airway epithelium from COPD patients. METHODS: The...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 33045470
DOI: 10.1016/j.ebiom.2020.103034

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