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Article

MiR-138 suppresses airway smooth muscle cell proliferation through the PI3K/AKT signaling pathway by targeting PDK1

7 Jul 2015

Abstract excerpt

BACKGROUND: Airway smooth muscle cells (ASMCs) play important physiological roles in the lung, and their abnormal proliferation directly contributes to airway remodeling during development of lung diseases such as asthma. MicroRNAs are small yet versatile gene tuners that regulate a variety of cellular processes, including cell growth and proliferation, but little is known about the precise role of microRNAs in...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26151666
DOI: 10.3109/01902148.2015.1041581

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