Article
Asthma inflammatory phenotypes show differential microRNA expression in sputum.
The Journal of allergy and clinical immunology - 1 May 2016
Maes Tania, Cobos Francisco Avila, Schleich Florence, Sorbello Valentina, Henket Monique, De Preter Katleen, Bracke Ken R, Conickx Griet, Mesnil Claire, Vandesompele Jo, Lahousse Lies, Bureau Fabrice, Mestdagh Pieter, Joos Guy F, Ricciardolo Fabio L M, Brusselle Guy G, Louis Renaud
Abstract excerpt
BACKGROUND: Asthma is classified according to severity and inflammatory phenotype and is likely to be distinguished by specific microRNA (miRNA) expression profiles. OBJECTIVE: We sought to associate miRNA expression in sputum supernatants with the inflammatory cell profile and disease severity in asthmatic patients. METHODS: We investigated miRNA expression in sputum supernatants of 10 healthy subjects, 17...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.