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RAB11-Mediated Trafficking and Human Cancers: An Updated Review

4 Jan 2021

Abstract excerpt

Many disorders block and subvert basic cellular processes in order to boost their progression. One protein family that is prone to be altered in human cancers is the small GTPase RAB11 family, the master regulator of vesicular trafficking. RAB11 isoforms function as membrane organizers connecting the transport of cargoes towards the plasma membrane with the assembly of autophagic precursors and the generation of...

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PMID: 33406725
DOI: 10.3390/biology10010026

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