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Article

Quantitation of JAK2 V617F Allele Burden by Using the QuantStudio™ 3D Digital PCR System.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Kinz Elena, Muendlein Axel

Abstract excerpt

The JAK2 V617F mutation is highly prevalent in patients with myeloproliferative neoplasms (MPN). Furthermore, it has been shown that its allelic burden correlates with hematologic characteristics, drug response, and clinical endpoints in MPN patients. Digital PCR is an emerging technology for sensitive mutation detection and quantitation, based on dilution and high-grade partitioning of a sample. Here, we...

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Identifiers

PMID: 29717448
DOI: 10.1007/978-1-4939-7778-9_15

Genes

JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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