Article
Clinical Implications of Quantitative JAK2 V617F Analysis using Droplet Digital PCR in Myeloproliferative Neoplasms.
Annals of laboratory medicine - 1 Mar 2018
Lee Eunyoung, Lee Kyoung Joo, Park Hyein, Chung Jin Young, Lee Mi Na, Chang Myung Hee, Yoo Jongha, Lee Hyewon, Kong Sun Young, Eom Hyeon Seok
Abstract excerpt
BACKGROUND: JAK2 V617F is the most common mutation in myeloproliferative neoplasms (MPNs) and is a major diagnostic criterion. Mutation quantification is useful for classifying patients with MPN into subgroups and for prognostic prediction. Droplet digital PCR (ddPCR) can provide accurate and reproducible quantitative analysis of DNA. This study was designed to verify the correlation of ddPCR with pyrosequencing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
