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Laboratory-developed Droplet Digital PCR Assay for Quantification of the JAK2V617F Mutation

1 Jan 2024

Abstract excerpt

Precise quantification of the JAK2 V617F mutation using highly sensitive assays is crucial for diagnosis, treatment process monitoring, and prognostic prediction in myeloproliferative neoplasms' (MPNs) patients. Digital droplet polymerase chain reaction (ddPCR) enables precise quantification of low-level mutations amidst a high percentage of wild type alleles without the need for external calibrators or...

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Share to Acute Myeloid Leukemia Research
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PMID: 38585044
DOI: 10.1055/s-0044-1785537

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