Digital Assays Part I: Partitioning Statistics and Digital PCR.

doi:10.1177/2472630317705680

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Article

Digital Assays Part I: Partitioning Statistics and Digital PCR.

SLAS technology - 1 Aug 2017

Basu Amar S

Abstract excerpt

A digital assay is one in which the sample is partitioned into many small containers such that each partition contains a discrete number of biological entities (0, 1, 2, 3, …). A powerful technique in the biologist's toolkit, digital assays bring a new level of precision in quantifying nucleic acids, measuring proteins and their enzymatic activity, and probing single-cell genotypes and phenotypes. Part I of this...

Topics

Circulating Tumor DNA
Data Interpretation, Statistical
Genotype
Polymerase Chain Reaction
RNA
Specimen Handling
Viral Load

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Open in PubMed

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PMID: 28448765
DOI: 10.1177/2472630317705680

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