Article
JAK2 V617F mutation can be reliably detected in serum using droplet digital PCR.
International journal of laboratory hematology - 1 Apr 2018
Nystrand C F, Ghanima W, Waage A, Jonassen C M
Abstract excerpt
INTRODUCTION: Detection of the JAK2 V617F mutation is a key step in the diagnosis of myeloproliferative neoplasms (MPN). Sensitive real-time quantitative PCR (qPCR) detection on peripheral blood (PB) is the most widely used method. The main objective of this study was to determine whether serum, the most common material available in archival biobanks, is a good liquid biopsy for detecting and quantifying the JAK2...
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