Article
[Research on Potential Role of Receptor-interacting Protein Kinase 1 in Phenotype Switching of Vascular Smooth Muscle Cells].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi - 1 Aug 2016
Bao Qinxue, Chen Li, Wu Siyuan, Zhao Mingyue, Wu Wenchao, Fu Hua, Liu Xiaojing
Abstract excerpt
Vascular smooth muscle cells(VSMCs)phenotype switching plays an essential role in the pathogenesis of various vascular diseases.The present study aims to investigate the role of receptor-interacting protein kinases 1(RIPK1)in VSMCs phenotypic switching induced by AngiotensinⅡ(AngⅡ).Expression of mRNA and protein of RIPK1,markers of VSMCs phenotypic switching and secretion,phosphorylation of the P65 subunit of...
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