Article
Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity
1 Jan 2020
Abstract excerpt
Vascular smooth muscle cells (VSMCs) play a pivotal role in the stability and tonic regulation of vascular homeostasis. VSMCs can switch back and forth between highly proliferative (synthetic) and fully differentiated (contractile) phenotypes in response to changes in the vessel environment. Abnormal phenotypic switching of VSMCs is a distinctive characteristic of vascular disorders, including atherosclerosis,...
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