Article
Intracellular Ca²⁺ signalling and phenotype of vascular smooth muscle cells.
Basic & clinical pharmacology & toxicology - 1 Jan 2012
Matchkov Vladimir V, Kudryavtseva Olga, Aalkjaer Christian
Abstract excerpt
Vascular smooth muscle cells (VSMCs) express considerable plasticity in their phenotype and even can change their phenotype in vivo depending on the functional demand. In addition to contractile phenotype, VSMCs can be proliferative, migrating and/or synthetic. Importantly, contractile and non-contractile phenotypes differ significantly in their intracellular Ca²⁺ signalling, which is a consequence of difference...
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