Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic switching of vascular smooth muscle cells in animal model of rat thoracic aortic aneurysm.

Interactive cardiovascular and thoracic surgery - 1 Jul 2015

Mao Naihui, Gu Tianxiang, Shi Enyi, Zhang Guangwei, Yu Lei, Wang Chun

Abstract excerpt

OBJECTIVES: To explore if there is phenotypic switching in the vascular smooth muscle cells (vSMCs) of rat thoracic aortic aneurysms and the role it plays in the process of aneurysm formation. METHODS: Male SD white rats were assigned randomly to the aneurysm group (AG) and control group (CG). The animal aneurysm model was obtained by soaking the peri-adventitia with porcine pancreatic elastase (PPE). The rats in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta, Thoracic
Share to Aortic Aneurysm, Thoracic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dilatation, Pathologic

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Myocytes, Smooth Muscle

Share to Myosin Heavy Chains

Share to Pancreatic Elastase

Source

Identifiers

PMID: 25829166
DOI: 10.1093/icvts/ivv074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic switching of vascular smooth muscle cells in animal model of rat thoracic aortic aneurysm.PMID 25829166Read ↗

Abdominal Aortic Aneurysm Formation with a Focus on Vascular Smooth Muscle CellsSemantic proximity Read ↗

Vascular smooth muscle cells in intracranial aneurysms.Semantic proximity Read ↗

Vascular Smooth Muscle Cells Phenotypic Switching in Cardiovascular Diseases.Semantic proximity Read ↗

Phenotypic switching of vascular smooth muscle cells in atherosclerosis, hypertension, and aortic dissection.Semantic proximity Read ↗

Phenotypic Switching of Vascular Smooth Muscle Cells in Atherosclerosis.Semantic proximity Read ↗

Dexmedetomidine protects cells from Angiotensin II-induced smooth muscle cell phenotype switch and endothelial cell dysfunction.Semantic proximity Read ↗

Human Umbilical Cord Mesenchymal Stem Cells Attenuate Abdominal Aortic Aneurysm Progression in Sprague-Dawley Rats: Implication of Vascular Smooth Muscle Cell Phenotypic Modulation.Semantic proximity Read ↗

Smooth muscle cell phenotypic diversity between dissected and unaffected thoracic aortic media.Semantic proximity Read ↗

SLC44A2-mediated phenotypic switch of vascular smooth muscle cells contributes to aortic aneurysm.Semantic proximity Read ↗

Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the activation of Krüppel-like factor 5.Semantic proximity Read ↗

FSTL1 protects against acute aortic dissection by suppressing vascular smooth muscle cell phenotypic switching and degradation of the extracellular matrix.Semantic proximity Read ↗

Metformin inhibits intracranial aneurysm formation and progression by regulating vascular smooth muscle cell phenotype switching via the AMPK/ACC pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.