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Article

High degree of concordance between flow cytometry and geno2pheno methods for HIV-1 tropism determination in proviral DNA.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000

Torres Alex José Leite, Brígido Luis Fernando de Macedo, Abrahão Marcos Herculano Nunes, Angelo Ana Luiza Dias, de Jesus Ferreira Gilcivaldo, Coelho Luana Portes, Ferreira João Leandro, Jorge Célia Regina Mayoral Pedroso, Netto Eduardo Martins, Brites Carlos

Abstract excerpt

Use of CCR5 antagonists requires previous viral tropism determination. The available methods have high cost, are time-consuming, or require highly trained personnel, and sophisticated equipment. We compared a flow cytometry-based tropism assay with geno2pheno method to determine HIV-1 tropism in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25701547
DOI: 10.1016/j.bjid.2014.11.007
PMCID: PMC9425389

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25701547-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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