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Article

The short-term improvements of enriched environment in behaviors and pathological changes of APP/PS1 mice via regulating cytokines.

Human vaccines & immunotherapeutics - 1 Jan 2018

Zhang Yuwei, Wang Ge, Wang Lin, Zhao Jian, Huang Rui, Xiong Qianying

Abstract excerpt

OBJECTIVE: To study the effect of enriched environment (EE) on cognitive function and pathological changes in Alzheimer's disease (AD) mice. METHOD: 6-month-old of the male mice were divided into 3 groups (n = 8), the wild type C57BL/6 mice in the control group, the APP/PS1 transgenic mice of AD reared in either the standard environment or the EE. Mice were feeding for 8 weeks, and then moved into standard...

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Source

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Identifiers

PMID: 29708824
DOI: 10.1080/21645515.2018.1463944
PMCID: PMC6149815

Genes

APP
BDNF
NGF
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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