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Article

Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody.

BioMed research international - 1 Jan 2018

Masui Kenta, Komori Takashi, Kato Yukinari, Masutomi Kenkichi, Ichimura Koichi, Ogasawara Satoshi, Kaneko Mika K, Oki Hiroharu, Suzuki Hiroyoshi, Nitta Masayuki, Maruyama Takashi, Muragaki Yoshihiro, Kawamata Takakazu, Sawada Tatsuo, Shibata Noriyuki

Abstract excerpt

Telomerase reverse transcriptase (TERT) is important for the biology of diffuse gliomas. TERT promoter mutations are selectively observed among 1p/19q-codeleted oligodendrogliomas and isocitrate dehydrogenase gene- (IDH-) wildtype glioblastoma (GBM). However, TERT transcripts range widely in various cancers including gliomas, and TERT protein expression has been rarely investigated thus far. It would be thus...

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Identifiers

PMID: 29693015
DOI: 10.1155/2018/7945845
PMCID: PMC5859900

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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