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Article

TERT Promoter Mutation Analysis to Distinguish Glioma From Gliosis.

Journal of neuropathology and experimental neurology - 1 Apr 2020

Hewer Ekkehard, Phour Jaison, Gutt-Will Marielena, Schucht Philippe, Dettmer Matthias S, Vassella Erik

Abstract excerpt

Among the most challenging diagnostic issues in surgical neuropathology is the distinction between scant infiltration by diffuse gliomas and reactive gliosis. The best documented ancillary marker to establish a definitive diagnosis of glioma in this setting is the identification of hotspot mutations in the isocitrate dehydrogenase 1 and 2 (IDH1/IDH2) genes, which is limited, however, by the low prevalence of...

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Identifiers

PMID: 32068851
DOI: 10.1093/jnen/nlaa004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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