Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications.

G3 (Bethesda, Md.) - 11 Apr 2023

Cornes Belinda K, Paisie Carolyn, Swanzey Emily, Fields Peter D, Schile Andrew, Brackett Kelly, Reinholdt Laura G, Srivastava Anuj

Abstract excerpt

Outbred laboratory mice (Mus musculus) are readily available and have high fecundity, making them a popular choice in biomedical research, especially toxicological and pharmacological applications. Direct high throughput genome sequencing (HTS) of these widely used research animals is an important genetic quality control measure that enhances research reproducibility. HTS data have been used to confirm the common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Heterozygote

Share to Homozygote

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 36649207
DOI: 10.1093/g3journal/jkad015
PMCID: PMC10085793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications.PMID 36649207Read ↗

Fifteen years of the Diversity Outbred mouse model: a review.Semantic proximity Read ↗

Characterization of a strain-specific CD-1 reference genome reveals potential inter- and intra-strain functional variabilitySemantic proximity Read ↗

High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs.Semantic proximity Read ↗

Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrainsSemantic proximity Read ↗

Characterization of a strain-specific CD-1 reference genome reveals potential inter- and intra-strain functional variability.Semantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.Semantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse modelsSemantic proximity Read ↗

Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype.Semantic proximity Read ↗

The Diversity Outbred mouse population.Semantic proximity Read ↗

The expanded BXD family of mice: A cohort for experimental systems genetics and precision medicineSemantic proximity Read ↗

Genomic characterization of the world's longest selection experiment in mouse reveals the complexity of polygenic traits.Semantic proximity Read ↗

Mouse protein coding diversity: What's left to discover?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.