Article
Genetic dissection of testis weight in mice: quantitative trait locus analysis using F(2) intercrosses between strains with extreme testis weight, and association study using Y-consomic strains.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2011
Suto Jun-Ichi
Abstract excerpt
In the present study, dissection of genetic bases of testis weight in mice was performed. Autosomes and the X chromosome were searched using traditional quantitative trait locus (QTL) scans, and the Y chromosome was searched by association studies of Y-consomic strains. QTL analysis was performed in ♀DDD × ♂CBA F(2) mice; the inbred mouse DDD has the heaviest testes, whereas the inbred mouse CBA has the lightest...
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