Article
The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism.
Translational stroke research - 1 Apr 2019
Ramos-Araque Maria E, Rodriguez Cristina, Vecino Rebeca, Cortijo Garcia Elisa, de Lera Alfonso Mercedes, Sanchez Barba Mercedes, Colàs-Campàs Laura, Purroy Francisco, Arenillas Juan F, Almeida Angeles, Delgado-Esteban Maria
Abstract excerpt
Cerebral preconditioning (PC) confers endogenous brain protection after stroke. Ischemic stroke patients with a prior transient ischemic attack (TIA) may potentially be in a preconditioned state. Although PC has been associated with the activation of pro-survival signals, the mechanism by which preconditioning confers neuroprotection is not yet fully clarified. Recently, we have described that PC-mediated...
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