Article
[Evaluation of the p53 Arg72Pro polymorphism as a prognostic factor in severe head injury and the inclusion of this indicator in a predictive model].
Revista espanola de anestesiologia y reanimacion - 1 Nov 2009
Martínez Lucas P, Carbayo Herencia J A, Moreno Cuesta J, Jordán J, García Cuesta D C, Escribano Martínez J
Abstract excerpt
BACKGROUND AND OBJECTIVE: Physiologic variables have traditionally been studied as prognostic factors in severe head injury. Until recently it was not thought that genetic factors might play a role. The main objective of this study was to construct a logistic regression model including physiologic variables and the p53 Arg72Pro polymorphism, which can promote neuron death through apoptosis. MATERIAL AND METHODS:...
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