Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury.

PloS one - 1 Jan 2014

Yildirim Ferah, Ji Shengbo, Kronenberg Golo, Barco Angel, Olivares Roman, Benito Eva, Dirnagl Ulrich, Gertz Karen, Endres Matthias, Harms Christoph, Meisel Andreas

Abstract excerpt

Epigenetic transcriptional regulation by histone acetylation depends on the balance between histone acetyltransferase (HAT) and deacetylase activities (HDAC). Inhibition of HDAC activity provides neuroprotection, indicating that the outcome of cerebral ischemia depends crucially on the acetylatio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Brain Ischemia
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CREB-Binding Protein

Share to Curcumin

Share to Gelsolin

Share to Gene Knockdown Techniques

Share to Histones

Source

Open in PubMed Open full text

Identifiers

PMID: 24748101
DOI: 10.1371/journal.pone.0095465
PMCID: PMC3991684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24748101-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury.PMID 24748101Read ↗

Epigenetic Regulation in Ischemic Neuroprotection: The Dual Role of HDACs and HATs in Neuroinflammation and RecoverySemantic proximity Read ↗

HDAC2 Selectively Regulates FOXO3a-Mediated Gene Transcription during Oxidative Stress-Induced Neuronal Cell DeathSemantic proximity Read ↗

Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic InjurySemantic proximity Read ↗

Exploring Histone Acetylation in Ischemic Stroke: The Role of CREBBP and CKAP4 as Key BiomarkersSemantic proximity Read ↗

Exploring Histone Acetylation in Ischemic Stroke: The Role of CREBBP and CKAP4 as Key BiomarkersSemantic proximity Read ↗

Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.Semantic proximity Read ↗

CREB: A Multifaceted Target for Alzheimer’s DiseaseSemantic proximity Read ↗

The Endoplasmic Reticulum Stress Response Factor CHOP-10 Protects against Hypoxia-induced Neuronal DeathSemantic proximity Read ↗

Therapeutic implications of phosphorylation- and dephosphorylation-dependent factors of cAMP-response element-binding protein (CREB) in neurodegenerationSemantic proximity Read ↗

Age-specific transcriptional response to stroke.Semantic proximity Read ↗

Genetic screen identified PRMT5 as a neuroprotection target against cerebral ischemia.Semantic proximity Read ↗

Histone acetylation in neuronal (dys)function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.