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Article

Genetic variation in biotransformation enzymes, air pollution exposures, and risk of spina bifida.

American journal of medical genetics. Part A - 1 May 2018

Padula Amy M, Yang Wei, Schultz Kathleen, Lurmann Fred, Hammond S Katharine, Shaw Gary M

Abstract excerpt

Spina bifida is a birth defect characterized by incomplete closure of the embryonic neural tube. Genetic factors as well as environmental factors have been observed to influence risks for spina bifida. Few studies have investigated possible gene-environment interactions that could contribute to spina bifida risk. The aim of this study is to examine the interaction between gene variants in biotransformation enzyme...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29681089
DOI: 10.1002/ajmg.a.38661
PMCID: PMC6320343

Genes

ABCC2
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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