Article
Folate Interaction With Genetic Risk for Neural Tube Defects Among Infants in Bangladesh.
Birth defects research - 1 Dec 2025
Mondragon-Estrada Enrique, Wang Xingyan, Uhler Michael D, Farooque Afifah, Liu Kelly, Mukherjee Sudipta Kumer, Ekramullah Sheikh Muhammad, Arman D M, Islam Joynul, Suchanda Hafiza Sultana, Christiani David C, Warf Benjamin C, Mazumdar Maitreyi, Morton Sarah U
Abstract excerpt
BACKGROUND: Neural tube defects such as spina bifida (SB) are congenital anomalies associated with significant morbidity and mortality worldwide. Environmental factors, particularly folate, modify SB risk. Based on recurrence rates of SB within families, genetic risk also contributes to SB development. However, the effect of maternal folate intake on genetic risk for SB in Bangladesh has not been quantified....
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