Article
Maternal genetic polymorphisms of phase II metabolic enzymes and the risk of fetal neural tube defects.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2014
Wang Linlin, Jin Lei, Liu Jufen, Zhang Yali, Yuan Yue, Yi Deqing, Ren Aiguo
Abstract excerpt
BACKGROUND: Maternal exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with the risk of fetal neural tube defects (NTDs). Whether maternal genetic variants related to PAH metabolism contribute to the development of fetal NTDs remains unclear. METHODS: We conducted a case-control study in a Chinese population to examine the association of selected maternal genetic variants of phase II enzymes...
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