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Article

Indoor air pollution and neural tube defects: effect modification by maternal genes.

Epidemiology (Cambridge, Mass.) - 1 Sept 2014

Wang Linlin, Li Zhiwen, Jin Lei, Li Kai, Yuan Yue, Fu Yunting, Zhang Yali, Ye Rongwei, Ren Aiguo

Abstract excerpt

BACKGROUND: Gene-environment interactions have been implicated in the development of neural tube defects (NTDs). METHODS: We conducted a case-control study to investigate (1) the association of aryl hydrocarbon receptor (AHR) genetic variants and phase I metabolic enzymes with the risk of NTDs and (2) the interaction of these variants with maternal exposure to indoor air pollution from smoking and coal combustion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25051309
DOI: 10.1097/EDE.0000000000000129

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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